Landon S, Smith P G, Staniek S P, Webber C E
Clin Chem. 1980 Jan;26(1):18-21.
Measurements of neck count-rates for personnel who regularly iodinated proteins with 125I showed that, generally, count rates were higher after iodination than before. The major pathway for the intake of 125I during iodination was through skin that was exposed to the free-iodine atmosphere of the fume hood. Neck count-rates were measured in 34 other subjects who were working with 125I. The rates for 25 of them were significantly greater than for a control group of 36 subjects. Significant activities were also detected in seven of nine subjects who had never worked directly with 125I but who were located within areas where it was used extensively. To minimize thyroid burdens of 125I, it is essential that neck count-rates be measured routinely, in order to monitor the safety of procedures involving the use of 125I.
对定期用¹²⁵I标记蛋白质的人员进行的颈部计数率测量表明,一般来说,碘化后的计数率高于碘化前。碘化过程中¹²⁵I摄入的主要途径是通过暴露于通风橱中游离碘气氛的皮肤。对其他34名使用¹²⁵I的受试者进行了颈部计数率测量。其中25人的计数率明显高于36名对照组受试者。在9名从未直接使用¹²⁵I但位于¹²⁵I广泛使用区域内的受试者中,也检测到了显著的放射性。为了尽量减少¹²⁵I对甲状腺的负担,必须定期测量颈部计数率,以监测涉及使用¹²⁵I的操作的安全性。