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大鼠慢肌和快肌去皮肤肌纤维中不同的等长力-[Ca2+]关系。

Different isometric force - [Ca2+] relationships in slow and fast twitch skinned muscle fibres of the rat.

作者信息

Stephenson D G, Forrest Q G

出版信息

Biochim Biophys Acta. 1980 Feb 8;589(2):358-62. doi: 10.1016/0005-2728(80)90052-3.

DOI:10.1016/0005-2728(80)90052-3
PMID:7356991
Abstract

Skinned muscle fibres prepared from fast and slow twitch muscles of rat have been activated in Ca2+-buffered solutions using a new activation procedure (Moisescu, D.G. and Thieleczek, R. (1978) J. Physiol. 275, 241--262). The results indicate that (i) the Ca2+ activation curve is less steep for slow fibres, (ii) physiologically relevant force levels are attained considerably faster at constant [Ca2+] in fast fibres, and (iii) active force becomes noticeable at lower [Ca2+], but reaches saturation at higher [Ca2+] for slow fibres.

摘要

利用一种新的激活程序(Moisescu, D.G.和Thieleczek, R.(1978年)《生理学杂志》275卷,241 - 262页),在Ca2 +缓冲溶液中激活了从大鼠的快肌和慢肌制备的去皮肌纤维。结果表明:(i)慢肌纤维的Ca2 +激活曲线较平缓;(ii)在快肌纤维中,在恒定[Ca2 +]条件下,生理相关的力水平达到得相当快;(iii)慢肌纤维在较低[Ca2 +]时主动力变得明显,但在较高[Ca2 +]时达到饱和。

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