Dosoretz D E, Blitzer P H, Wang C C, Linggood R M
Cancer. 1980 Mar 15;45(6):1467-71. doi: 10.1002/1097-0142(19800315)45:6<1467::aid-cncr2820450628>3.0.co;2-#.
The records of 20 patients with biopsy-proven glioma of the optic nerve and chiasm are reviewed. Symptoms and physical findings on admission are reported. Patients were classified, according to the operative findings, into disease limited to the optic nerve and a more extensive disease group. Surgical procedures, operative complications, irradiation technique, and outcome are analyzed. Patients with disease limited to the optic nerve may be adequately managed by resection alone. In the more extensive lesions, high morbidity is associated with resection; therefore, biopsy and irradiation offer the best alternatives for this group of patients.
回顾了20例经活检证实为视神经及视交叉胶质瘤患者的记录。报告了入院时的症状和体格检查结果。根据手术所见,将患者分为病变局限于视神经组和病变范围更广组。分析了手术方式、手术并发症、放疗技术及治疗结果。病变局限于视神经的患者单纯行切除术可能即可得到充分治疗。对于病变范围更广的患者,手术切除的并发症发生率较高;因此,活检及放疗是这类患者的最佳选择。