Sheridan P J, Herbert D C
Cell Tissue Res. 1980;206(1):35-40. doi: 10.1007/BF00233605.
Castrated adult male hamsters and castrated adult female rats were injected with either 0.2 microgram (hamsters) or 0.5 microgram (rats) of 3H-dihydrotestosterone (107 Ci/mmole)/100 grams body weight and killed 1 1/2 h later. The pituitary glands were removed and processed for both autoradiography and immunocytochemistry (hamster) or only autoradiography (rats). Localization of the androgen was found in 10-15% of the cells of the pars distalis in both species. Only cells that stained for luteinizing hormone (LH) in the hamster's pars distalis concentrated the androgen. Also cells in both the pars intermedia and pars nervosa (1-5%) concentrated the androgen in both species. Although the number of cells that concentrated the androgen in the pars intermedia and pars nervosa was small, this finding may be related to recent physiologic data that suggest that the gonadal steroids may play a role in regulating water retention and natriuresis.
对成年去势雄性仓鼠和成年去势雌性大鼠分别注射0.2微克（仓鼠）或0.5微克（大鼠）的3H-双氢睾酮（107居里/毫摩尔）/100克体重，1个半小时后处死。取出垂体，用于放射自显影和免疫细胞化学分析（仓鼠）或仅用于放射自显影（大鼠）。在两个物种的远侧部10%-15%的细胞中发现了雄激素的定位。在仓鼠远侧部，仅对促黄体生成素（LH）染色的细胞聚集了雄激素。在两个物种中，中间部和神经部的细胞（1%-5%）也聚集了雄激素。尽管中间部和神经部聚集雄激素的细胞数量较少，但这一发现可能与近期的生理学数据有关，这些数据表明性腺类固醇可能在调节水潴留和利钠作用中发挥作用。
