• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

手术治疗骨折后骨髓炎。62例采用根治性手术及林可霉素(洁霉素)治疗的报告。

Osteomyelitis after operative fracture treatment. A report of 62 cases treated with radical surgery and lincomycin (Lincocin).

作者信息

Hagen R

出版信息

Acta Orthop Scand. 1978 Dec;49(6):542-8. doi: 10.3109/17453677808993235.

DOI:10.3109/17453677808993235
PMID:735780
Abstract

During the years 1967--1975 a total of 62 patients were treated for postoperative osteomyelitis. The lower extremities had been fractured in 89 per cent of the cases and 54 per cent were closed injuries. The fractures, mostly caused by traffic accidents and falls, had been immobilized by plates in 30 and by intramedullary nails or pins in 25 patients. Staphylococcus aureus was cultured in 80 per cent, 68 per cent of them were resistant to penicillin, but in 84 per cent the organisms were highly lincomycin sensitive and only three patients with four osteomyelitic lesions presented lincomycin resistance. The treatment consisted chiefly of sequestrectomies and saucerizations supported by 3--12 months of lincomycin treatment. In 30 operations a closed irrigation-suction technique was used, perfusing the wound with lincomycin solution. Stable implants should be left in place until the fracture is clinically solid whereas unstable osteosyntheses should be replaced by rigid internal or extraskeletal fixation. At follow-up, the results were judged as good in 74 per cent, fair 8 per cent and poor 18 per cent. The amputation rate was 13 per cent. Plates should not be used in the treatment of comminuted tibial fractures with considerable soft tissue damage.

摘要

1967年至1975年期间,共有62例患者接受了术后骨髓炎的治疗。其中89%的病例下肢骨折,54%为闭合性损伤。骨折大多由交通事故和跌倒所致,30例患者采用钢板固定,25例患者采用髓内钉或钢针固定。80%的病例培养出金黄色葡萄球菌,其中68%对青霉素耐药,但84%的菌株对林可霉素高度敏感,仅有3例患者的4处骨髓炎病灶对林可霉素耐药。治疗主要包括死骨切除术和碟形手术,并辅以3至12个月的林可霉素治疗。30例手术采用闭合冲洗吸引技术,用林可霉素溶液灌注伤口。稳定的内固定物应保留至骨折临床愈合,而不稳定的骨固定术则应更换为坚强的内固定或外固定。随访时,74%的结果评定为良好,8%为一般,18%为差。截肢率为13%。对于伴有严重软组织损伤的粉碎性胫骨骨折,不应使用钢板治疗。

相似文献

1
Osteomyelitis after operative fracture treatment. A report of 62 cases treated with radical surgery and lincomycin (Lincocin).手术治疗骨折后骨髓炎。62例采用根治性手术及林可霉素(洁霉素)治疗的报告。
Acta Orthop Scand. 1978 Dec;49(6):542-8. doi: 10.3109/17453677808993235.
2
Open fracture of the tibia in children.儿童胫骨开放性骨折
J Bone Joint Surg Am. 1996 Jul;78(7):1039-47. doi: 10.2106/00004623-199607000-00008.
3
Treatment of long bone osteomyelitis with a mechanically stable intramedullar antibiotic dispenser: nineteen consecutive cases with a minimum of 12 months follow-up.使用机械稳定的髓内抗生素给药装置治疗长骨骨髓炎:连续19例,至少随访12个月。
J Trauma. 2008 Dec;65(6):1416-20. doi: 10.1097/TA.0b013e31818c6a09.
4
[Experiences with lincomycin in surgery].
Arzneimittelforschung. 1969 May;19(5):769-74.
5
Tibial shaft fractures. A comparison of conservative treatment and internal fixation with conventional plates or AO compression plates.胫骨干骨折。保守治疗与使用传统钢板或AO加压钢板内固定的比较。
Acta Orthop Scand. 1977;48(2):204-12. doi: 10.3109/17453677708985136.
6
Chronic osteomyelitis. A report of fifty cases treated with lincomycin (Lincocin).慢性骨髓炎。林可霉素(洁霉素)治疗50例报告。
Acta Orthop Scand. 1971;42(4):320-7. doi: 10.3109/17453677108989052.
7
Treatment of chronic osteomyelitis; a prospective study of 55 cases treated with radical surgery and primary wound closure.
Acta Orthop Scand. 1982 Oct;53(5):715-20. doi: 10.3109/17453678208992282.
8
[Results of 10 years of use of lincomycin (1966-1976) in the clinics of the N. N. Priorov Central Research Institute of Traumatology and Orthopedics].
Antibiotiki. 1978 Mar;23(3):268-72.
9
[Various methods of using lincomycin for treating acute and chronic hematogenic osteomyelitis in children].
Antibiotiki. 1977 Aug;22(8):749-53.
10
[Isolated fracture of the ulnar diaphysis, from plate osteosynthesis to intramedullary nailing].[尺骨干单骨折,从钢板内固定到髓内钉固定]
Rev Chir Orthop Reparatrice Appar Mot. 1998 Oct;84(6):515-22.