Trigueros A P, Vazquez V, De Miguel G F
Acta Orthop Scand. 1978 Dec;49(6):582-8. doi: 10.3109/17453677808993241.
Three cases are presented of the very rare Larsen's syndrome, being only the second report in the literature of concomitant involvement of parent (the mother in this instance) and offspring (two children) (see also Haberman et al. 1976). The only therapeutic procedure that is applicable, i.e., surgery, has given only mediocre results over an evolutive period of 8 to 9 years (in case C). We have not been able to demonstrate analytical or histological abnormalities that might provide a diagnostic clue, so that the aetiopathogeny of the disorder remains unknown.
本文报告了3例极为罕见的拉森综合征，这是文献中第二例关于父母（此例为母亲）和子女（两个孩子）同时患病的报道（另见哈伯曼等人，1976年）。唯一适用的治疗方法即手术，在8至9年的病程中（病例C）效果一般。我们未能发现可能提供诊断线索的分析或组织学异常，因此该疾病的病因仍不清楚。
