利用富含分裂形态的鼠锥虫群体吸收小鼠血清中的抑殖活性。
Absorption of ablastic activity from mouse serum by using a Trypanosoma musculi population rich in dividing forms.
作者信息
Brooks B O, Reed N D
出版信息
Infect Immun. 1980 Jan;27(1):94-6. doi: 10.1128/iai.27.1.94-96.1980.
Abstract
An in vivo assay of ablastin activity was developed by passive transfer of ablastic serum into nude mice. Preparations of Trypanosoma musculi that contained 35 to 50% dividing forms removed ablastic activity from mouse serum, but absorption of serum with a parasite preparation consisting of less than 5% dividing forms did not appreciably alter ablastic activity. These data suggest that ablastin is an antibody that can be absorbed onto homologous trypanosomes.
摘要
通过将无增殖素血清被动转移至裸鼠体内，开发出一种无增殖素活性的体内测定方法。含有35%至50%分裂型的鼠锥虫制剂可去除小鼠血清中的无增殖素活性，但用分裂型少于5%的寄生虫制剂吸收血清并不会显著改变无增殖素活性。这些数据表明，无增殖素是一种可吸附于同源锥虫上的抗体。
相似文献
1
Absorption of ablastic activity from mouse serum by using a Trypanosoma musculi population rich in dividing forms.利用富含分裂形态的鼠锥虫群体吸收小鼠血清中的抑殖活性。
Infect Immun. 1980 Jan;27(1):94-6. doi: 10.1128/iai.27.1.94-96.1980.
2
Chronic infection with Trypanosoma musculi in congenitally athymic nude mice.先天性无胸腺裸鼠的小鼠锥虫慢性感染。
Infect Immun. 1977 May;16(2):715-6. doi: 10.1128/iai.16.2.715-716.1977.
3
Kinetics of immunoglobulin M and G responses of nude and normal mice to Trypanosoma musculi.裸鼠和正常小鼠对小鼠锥虫免疫球蛋白M和G反应的动力学
Infect Immun. 1982 May;36(2):667-71. doi: 10.1128/iai.36.2.667-671.1982.
4
Identification of antibody classes and Fc receptors responsible for phagocytosis of Trypanosoma musculi by mouse macrophages.鉴定负责小鼠巨噬细胞吞噬肌肉锥虫的抗体类别和Fc受体。
Infect Immun. 1986 Sep;53(3):600-5. doi: 10.1128/iai.53.3.600-605.1986.
5
The cell surface of Trypanosoma musculi bloodstream forms. II. Lectin and immunologic studies.鼠锥虫血流型的细胞表面。II. 凝集素和免疫学研究。
J Protozool. 1976 May;23(2):262-71. doi: 10.1111/j.1550-7408.1976.tb03767.x.
6
Immune and nonimmune regulation of the population of Trypanosoma musculi in infected host mice.感染宿主小鼠中肌肉锥虫群体的免疫和非免疫调节
Infect Immun. 1990 Jun;58(6):1757-62. doi: 10.1128/iai.58.6.1757-1762.1990.
7
Elicitation of the reproduction-inhibiting antibody ablastin by serum exoantigens of Trypanosoma lewisi.路氏锥虫血清外抗原诱导产生抑制生殖抗体抗殖素
J Parasitol. 1986 Dec;72(6):939-43.
8
Ablastin: antigen tolerance and lack of ablastin control of Trypanosoma musculi during host's pregnancy.抑殖素：宿主怀孕期对肌肉锥虫的抗原耐受性及抑殖素调控缺失
Exp Parasitol. 1975 Dec;38(3):317-21. doi: 10.1016/0014-4894(75)90117-4.
9
The role of natural agglutinins and trypanolytic activity in host specificity of Trypanosoma musculi.天然凝集素和锥虫溶解活性在小鼠锥虫宿主特异性中的作用。
Parasite Immunol. 1984 Nov;6(6):509-17. doi: 10.1111/j.1365-3024.1984.tb00821.x.
10
Trypanosoma musculi infections in normocomplementemic, C5-deficient, and C3-depleted mice.正常补体、C5缺陷和C3缺失小鼠中的鼠锥虫感染。
Infect Immun. 1977 May;16(2):557-63. doi: 10.1128/iai.16.2.557-563.1977.
引用本文的文献
1
Kinetics of immunoglobulin M and G responses of nude and normal mice to Trypanosoma musculi.裸鼠和正常小鼠对小鼠锥虫免疫球蛋白M和G反应的动力学
Infect Immun. 1982 May;36(2):667-71. doi: 10.1128/iai.36.2.667-671.1982.
2
Trypanosoma musculi infection in B-cell-deficient mice.B细胞缺陷小鼠中的鼠锥虫感染。
Infect Immun. 1984 Apr;44(1):162-7. doi: 10.1128/iai.44.1.162-167.1984.
3
Immune and nonimmune regulation of the population of Trypanosoma musculi in infected host mice.感染宿主小鼠中肌肉锥虫群体的免疫和非免疫调节
Infect Immun. 1990 Jun;58(6):1757-62. doi: 10.1128/iai.58.6.1757-1762.1990.
本文引用的文献
1
The effects of X or neutron irradiation, India ink blockade, or splenectomy on innate immunity against Trypanosoma duttoni in mice.X射线或中子辐射、印度墨汁阻断或脾切除对小鼠抗杜氏锥虫天然免疫的影响。
J Infect Dis. 1959 Mar-Apr;104(2):119-29. doi: 10.1093/infdis/104.2.119.
2
Virulent Trypanosoma lewisi infections in cortisone-treated rats.
J Parasitol. 1967 Apr;53(2):258-62.
3
On the life cycle of trypanosomes of the lewisi group and their relationships to other mammalian trypanosomes.
Rev Inst Med Trop Sao Paulo. 1969 Jan-Feb;11(1):34-43.
4
5
Immunological studies of nude mice.裸鼠的免疫学研究。
Contemp Top Immunobiol. 1974;3:243-63. doi: 10.1007/978-1-4684-3045-5_10.
6
Trypanosoma musculi infections in complement-deficient mice.
Exp Parasitol. 1975 Apr;37(2):205-10. doi: 10.1016/0014-4894(75)90071-5.
7
The immunological response of CBA mice to Trypanosoma musculi: elimination of the parasite from the blood.
Int J Parasitol. 1975 Apr;5(2):231-4. doi: 10.1016/0020-7519(75)90034-x.
8
Immunosuppression and ablastin.免疫抑制与抑殖素
Exp Parasitol. 1975 Dec;38(3):322-37. doi: 10.1016/0014-4894(75)90118-6.
9
Ablastin: the phenomenon.抑殖素：该现象
Exp Parasitol. 1975 Dec;38(3):303-8. doi: 10.1016/0014-4894(75)90115-0.
10
The immunological response of CBA mice to Trypanosoma musculi: mechanisms of protective immunity.CBA小鼠对鼠锥虫的免疫反应：保护性免疫机制
Int J Parasitol. 1975 Apr;5(2):235-9. doi: 10.1016/0020-7519(75)90112-5.
Zotero 插件