Chatal J F, Chabay C, Weber J, Vasseur E, Guihard D
J Radiol Electrol Med Nucl. 1977 Aug-Sep;58(8-9):519-24.
The combined interest of thermography and 99mTc Bleomycin scintigraphy in the differential diagnosis of a cold thyroid nodule was evaluated in 86 patients. In all cases a histological examination was performed. Of the 30 malignant nodules (clinically suspect and solitary nodules) 21 (70%) showed concentrations of 99mTc Bleomycin while only 7 of the 12 solitary malignant nodules did so. Among the 54 benign nodules the false positive rate was 54%. Thermography was positive in 26 (87%) of the 30 malignant nodules and in only 8 (67%) of the 12 solitary malignant nodules. For the 54 benign nodules the false positive rate was 72%. The combined results of the study do not provide any improvement in diagnostic accuracy. Thus it can be said that applications of 99mTc Bleomycin and thermography in the diagnosis of solitary hypofixiant nodules are of limited value.
对86例患者评估了热成像和99mTc博来霉素闪烁扫描在冷甲状腺结节鉴别诊断中的联合应用价值。所有病例均进行了组织学检查。在30个恶性结节（临床可疑且为孤立性结节）中，21个（70%）显示99mTc博来霉素浓聚，而12个孤立性恶性结节中只有7个如此。在54个良性结节中，假阳性率为54%。热成像在30个恶性结节中的26个（87%）呈阳性，在12个孤立性恶性结节中只有8个（67%）呈阳性。对于54个良性结节，假阳性率为72%。该研究的联合结果在诊断准确性方面未提供任何改善。因此可以说，99mTc博来霉素和热成像在孤立性低摄取结节诊断中的应用价值有限。
