Dillon T, Meyer R A, Korfhagen J C, Kaplan S, Chung K J
J Pediatr. 1980 Mar;96(3 Pt 2):552-8. doi: 10.1016/s0022-3476(80)80865-1.
Serial echocardiograms of five children who had infective endocarditis were analyzed and correlated with the clinical course. Vegetations were visualized initially on M-mode in four and on two-dimensional echocardiograms in all patients. The appearance of the vegetation was unexpected in one. More accurate anatomic localization of the vegetation was possible using two-dimensional echography. Four of the five patients died despite vigorous medical treatment and valve replacement in two. Complete resolution of the vegetation was documented for the first time in a child following medical therapy. This study suggests that echocardiography plays an important role in the diagnosis of endocarditis, allows objective follow-up of the size of the vegetations and their effects on valve function, and, therefore, may prove helpful in the management of these patients.
对5例感染性心内膜炎患儿的系列超声心动图进行了分析，并与临床病程进行了关联。4例患儿最初在M型超声心动图上观察到赘生物，所有患儿在二维超声心动图上均观察到赘生物。1例患儿赘生物的表现出乎意料。使用二维超声心动图可以更准确地对赘生物进行解剖定位。5例患儿中有4例尽管积极接受药物治疗，其中2例还进行了瓣膜置换，但仍死亡。首次记录到1例患儿在接受药物治疗后赘生物完全消退。本研究表明，超声心动图在感染性心内膜炎的诊断中起重要作用，能够客观地随访赘生物大小及其对瓣膜功能的影响，因此可能有助于这些患者的治疗。
