在胚胎早期滞育期间用醋酸甲羟孕酮处理的水貂（鼬属）中的高级着床。

Advanced implantation in mink (Mustela vison) treated with medroxyprogesterone acetate during early embryonic diapause.

作者信息

Concannon P, Pilbeam T, Travis H

出版信息

J Reprod Fertil. 1980 Jan;58(1):1-6. doi: 10.1530/jrf.0.0580001.

DOI:10.1530/jrf.0.0580001

Abstract

Adult and pubertal female mink mated on 4 March were administered 2.5 mg medroxyprogesterone acetate (MPA) or control vehicle on 9-11 March. Pregnancies were shorter (P less than 0.01) in adult (60 +/- 2 days) than in pubertal (72 +/- 0.7 days) control animals. Treatment with MPA reduced (P less than 0.01) the length of pregnancy in both adult (51 +/- 1 days) and pubertal (60 +/- 2 days) mink but did not significantly affect serum progesterone levels on 3-4 April. Observations at laparotomy during April confirmed the effects of age and treatment on the time of implantation and suggested that implantation sites become grossly visible 28 days before parturition. It is concluded that administration of a progestagen during early embryonic diapause can advance the time of implantation in mink.

摘要

3月4日交配的成年和青春期雌性水貂于3月9日至11日接受2.5毫克醋酸甲羟孕酮（MPA）或对照赋形剂处理。成年对照动物（60±2天）的妊娠期短于青春期对照动物（72±0.7天）（P<0.01）。MPA处理缩短了成年（51±1天）和青春期（60±2天）水貂的妊娠期（P<0.01），但对4月3日至4日的血清孕酮水平无显著影响。4月剖腹探查的观察结果证实了年龄和处理对着床时间的影响，并表明着床部位在分娩前28天变得肉眼可见。结论是，在早期胚胎滞育期间给予孕激素可提前水貂的着床时间。