前列腺素A-1、E-2和F-2α对大鼠精子发生的影响。
Effect of prostaglandins A-1, E-2 and F-2 alpha on spermatogenesis in rats.
作者信息
Didolkar A K, Roychowdhury D
出版信息
J Reprod Fertil. 1980 Jan;58(1):275-8. doi: 10.1530/jrf.0.0580275.
PMID:7359486
Abstract
Rats were treated with twice daily injections of 100 microgram PG/rat for 15 days. PGA-1 had no effect. PGE-2 caused a significant increase in testicular weight, RNA content, hyaluronidase activity and number of spermatids. PGF-2 alpha produced a significant decrease in sorbitol dehydrogenase activity and DNA content. It is suggested that PGE-2 may be involved in later stages of spermatogenesis, i.e. conversion of spermatocytes to spermatids.
摘要
给大鼠每日注射两次，每次100微克PG/大鼠，共注射15天。PGA - 1无作用。PGE - 2使睾丸重量、RNA含量、透明质酸酶活性和精子细胞数量显著增加。PGF - 2α使山梨醇脱氢酶活性和DNA含量显著降低。提示PGE - 2可能参与精子发生的后期阶段，即精母细胞向精子细胞的转化。
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