Bird R J, Bryce D P
J Otolaryngol. 1980 Feb;9(1):18-23.
The longterm effects of heavy irradiation to the neck are now well known. The literature contains reports of major skin contractures, hypothyroidism, laryngeal and tracheal stenosis, major vessel stenosis, and hypoplastic development of cervical vertebrae, but very rarely are all these complications seen in a single patient. Two patients have undergone extensive treatment at the Toronto General Hospital during the past decade for complications of neck irradiation in childhood and their stories should serve as yet another reminder that irradiation, although a major ally in oncological therapy when carefully applied, can be a tool of great destruction when used in excess.
颈部大剂量辐射的长期影响如今已为人熟知。文献中有关于严重皮肤挛缩、甲状腺功能减退、喉和气管狭窄、大血管狭窄以及颈椎发育不全的报道，但这些并发症极少在同一患者身上全部出现。在过去十年间，有两名患者因童年时期颈部放疗的并发症在多伦多综合医院接受了广泛治疗，他们的经历应再次提醒人们，放疗尽管在谨慎应用时是肿瘤治疗的主要手段，但使用过度时可能成为极具破坏力的工具。
