[Pathophysiological aspects of the venous hemodynamics in acute thrombosis of the deep veins and in the postthrombophlebitic syndrome of the lower extremities and pelvis].

The systemic, regional, and microcirculatory hemodynamics was studied complexly by radioisotope methods in 54 patients with acute thrombosis of the deep veins of the lower limbs and pelvis and in 58 patients with the postthrombophlebitic syndrome. It is shown that in acute venous thrombosis the regional stasis and hypertension are attended by considerable deposits of blood in the "affected" limb with a decrease in the venous return to the heart and disturbance of transcapillary exchange. In the postthrombotic syndrome the pathogenetic importance of venous stasis and hypertension is maintained both in the stage of occlusion and in the stage of recanalization. In this case, the hemodynamic changes in the edematous-algesic form differ from those in the edematous-ulcerative form. It is established that occlusion of the ilio-femoral-popliteal-tibial segment in acute venous thrombosis and postthrombophlebitic syndrome is characterized by the most pronounced shifts in regional hemodynamics.