Ivanov L A, Chebotarev N D
Kosm Biol Aviakosm Med. 1980 Jan-Feb;14(1):39-42.
In 9 normal test subjects, aged 19-32, pO2, pCO2 and pH of arterial and venous blood were measured. The curve of oxyhemoglobin dissociation during 20 min inhalation of a 95% O2 containing mixture was analyzed. The studies demonstrate that during hyperoxia there is a shift to the left of the dissociation curve in native blood and standard curve (i.e. normalized to pH 7.4). This shift of the curve of oxyhemoglobin dissociation indicating an increase in hemoglobin affinity for oxygen seems to be one of the factors responsible for an increase in the pO2 arteriovenous difference and a much lower increment of venous pO2 than that of arterial pO2.
在9名年龄为19 - 32岁的正常受试对象中，测量了动脉血和静脉血的氧分压（pO2）、二氧化碳分压（pCO2）及pH值。分析了吸入含95%氧气的混合气体20分钟期间氧合血红蛋白解离曲线。研究表明，在高氧期间，天然血液和标准曲线（即标准化至pH 7.4）的解离曲线向左移动。氧合血红蛋白解离曲线的这种移动表明血红蛋白对氧的亲和力增加，这似乎是导致动脉血氧分压差增加以及静脉血氧分压增加值远低于动脉血氧分压增加值的因素之一。
