Michaelis R, Haug S, Majewski F, Bierich J R, Dopfer R
Monatsschr Kinderheilkd (1902). 1980 Jan;128(1):21-6.
The histories of mothers addicted to chronic abuse of alcohol always present severe complications during pregnancy and for most of their children during the peri- and postnatal period as well. The question arises to what extent peri- and postnatal complications may influence the clinical aspect of the alcoholembryopathy (AE) in these children. In 35 children with AE all details of their histories could be traced. By using Prechtl's concept of optimal conditions two different populations could be found amongst the children with AE, one with and the other without severe peri- and postnatal complications (exclusively peri- and postnatal asphyxia). No correlation could be found between the severity of AE and perinatal asphyxia. The result suggests reservation in rating peri- and posnatal asphyxia as an always potent factor causing brain damage.
长期酗酒成瘾的母亲在孕期以及她们的大多数孩子在围产期和产后都会出现严重并发症。问题在于围产期和产后并发症在多大程度上会影响这些孩子酒精胚胎病（AE）的临床症状。在35例患有AE的儿童中，可以追溯到他们病史的所有细节。通过运用普雷希特关于最佳条件的概念，在患有AE的儿童中发现了两个不同的群体，一组有严重的围产期和产后并发症（仅围产期和产后窒息），另一组没有。AE的严重程度与围产期窒息之间没有相关性。该结果表明，在将围产期和产后窒息评定为导致脑损伤的始终有效的因素时应持保留态度。
