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二尖瓣狭窄手术矫正后出现严重心源性溶血性贫血伴红细胞柔韧性降低(作者译)

[Severe cardiogenic hemolytic anemia with decreased flexibility of erythrocytes following surgical correction of mitral valve stenosis (author's transl)].

作者信息

Tillmann W, Dähn D, Hellberg K

出版信息

Monatsschr Kinderheilkd (1902). 1980 Feb;128(2):81-3.

PMID:7360137
Abstract

After surgical correction of a common atrium and closure of a mitral cleft, a mitral stenosis developed in a 5 year old girl. Postoperatively a pronounced hemolysis developed necessitating multiple blood transfusions. Rheologic measurements showed that hemolysis was due to a loss of erythrocyte deformability after mechanical damage. On the basis of these measurements it was concluded that the mitral stenosis was most likely responsible for this mechanical damage. Following another surgical correction of the mitral valve there was no hemolysis anymore.

摘要

在对一名5岁女孩进行共同心房手术矫正并闭合二尖瓣裂后,出现了二尖瓣狭窄。术后发生了明显的溶血,需要多次输血。流变学测量表明,溶血是由于机械损伤后红细胞变形能力丧失所致。基于这些测量结果得出结论,二尖瓣狭窄很可能是造成这种机械损伤的原因。在对二尖瓣进行另一次手术矫正后,不再有溶血现象。

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