Kadota K, Sasahira M, Hamada H, Awa H, Matsuda K, Asakura T
No Shinkei Geka. 1980 Feb;8(2):173-9.
A case of chordoma was reported with a special reference to the computed tomography. A 22-year-old female, who had been in good health, was admitted to Kagoshima University Hospital on December 8, 1978 with a chief complaint of diplopia. Physical examination was nothing particular and neurologic examination revealed the left abducent nerve palsy. The labolatory findings including blood count, serum electrolytes, hormonal study, carcinoembrynonic antigen (CEA) and alpha-fetoprotein were within normal limits. Plain skull filsm showed a retro-sellar calcification in combination with a bony erosion of the dorsum sellae and the clivus. The left vertebral arteriography and the left carotid arteriography showed a space taking lesion extended from the retro-clival to the left parasellar region. The axial CT scanning showed a round and irregular high density area consistent with calcification, at the retro-clival area, middle cranial fossa, and parasellar region in the left side, and no enhancement effect was acquired. The coronal CT appearance showed a round but discontinuous high density area like a coral reef, based on the clivus. These CT findings indicated the extension of the space taking legion, clearly. Intra-capsular removal of the tumor was performed and histologic examination confirmed the chordoma. It will be emphasized that CT scan, particularly coronal section was one of the most useful diagnostic procedure of amss of the skull base.
报告了1例脊索瘤病例，并特别提及计算机断层扫描。一名22岁健康女性，因复视为主诉于1978年12月8日入住鹿儿岛大学医院。体格检查无特殊异常，神经系统检查发现左侧展神经麻痹。包括血常规、血清电解质、激素检查、癌胚抗原（CEA）和甲胎蛋白在内的实验室检查结果均在正常范围内。头颅平片显示蝶鞍后钙化，伴有蝶鞍背和斜坡骨质侵蚀。左侧椎动脉造影和左侧颈动脉造影显示一个占位性病变，从斜坡后延伸至左侧鞍旁区域。轴向CT扫描显示左侧斜坡后区、中颅窝和鞍旁区域有一个圆形不规则高密度区，与钙化相符，且无强化效应。冠状位CT表现显示一个基于斜坡的圆形但不连续的高密度区，类似珊瑚礁。这些CT表现清楚地显示了占位性病变的范围。对肿瘤进行了囊内切除，组织学检查证实为脊索瘤。需要强调的是，CT扫描，尤其是冠状位扫描是颅底肿物最有用的诊断方法之一。
