Vidal B, Candia C, Carollo C
Minerva Med. 1980 Feb 25;71(6):411-8.
The hand, and the phalanges in particular, offer a privileged observation ground for the study of some features of bone metabolism. An account is given of the cell alterations from which the various disturbances associated with osteogenesis and osteolysis can be recognized, particular attention being devoted to changes in bone density, cortex thickness, and the structure of the spongy substance. Evaluation of these three parameters will lead to the recognition of porosis, malacia, hyperosteolysis, and osteomyelosclerosis. When combined with certain clinical and laboratory data, the findings can readily be used to reach an exact diagnosis.