Fujii S, Okamura H, Nakashima N, Bann C, Aso T, Nishimura T
Obstet Gynecol. 1980 Mar;55(3 Suppl):79S-83S. doi: 10.1097/00006250-198003001-00025.
The ninth documented case of leiomyomatosis peritonealis disseminata (LPD) combined with pregnancy is presented. Light and electron microscopic studies revealed that the smaller tumors were composed partly of decidual cells and partly of fibroblasts, and the larger tumors contained cells resembling smooth muscle cells. Plasma steroid levels were determined during pregnancy. Estrogen levels were within normal range, but progesterone levels were lower than normal, resulting in relative hyperestrogenism. In the case presented, pregnancy, especially with relative hyperestrogenism, may have been a major cause of LPD.
本文报告了第九例腹膜播散性平滑肌瘤病（LPD）合并妊娠的病例。光镜和电镜研究显示，较小的肿瘤部分由蜕膜细胞组成，部分由成纤维细胞组成，而较大的肿瘤含有类似平滑肌细胞的细胞。在孕期测定了血浆类固醇水平。雌激素水平在正常范围内，但孕酮水平低于正常，导致相对雌激素过多。在本病例中，妊娠，尤其是相对雌激素过多，可能是LPD的主要病因。
