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肾上腺腺瘤所致儿童原发性醛固酮增多症:肾上腺静脉插管术前定位

Childhood primary aldosteronism due to an adrenal adenoma: preoperative localization by adrenal vein catheterization.

作者信息

Ganguly A, Bergstein J, Grim C E, Yum M N, Weinberger M H

出版信息

Pediatrics. 1980 Mar;65(3):605-9.

PMID:7360550
Abstract

Primary aldosteronism resulting from an adrenal adenoma is rare in children. An 8 1/2-year-old girl was found to have hypertension and spontaneous hypokalemia, both detected as incidental findings. Subsequent investigations revealed inappropriately elevated levels of plasma and urinary aldosterone with suppressed plasma renin activity. Adrenal vein blood sampling and venography suggested the presence of left adrenal adenoma which was confirmed at surgical exploration and pathologic examination. All the clinical and biochemical abnormalities were corrected by the adrenalectomy. The differential diagnoses of various types of hyperaldosteronism and/or hypokalemia in such a clinical setting are discussed.

摘要

由肾上腺腺瘤引起的原发性醛固酮增多症在儿童中罕见。一名8岁半女孩被发现患有高血压和自发性低钾血症,均为偶然发现。随后的检查显示血浆和尿醛固酮水平异常升高,血浆肾素活性受到抑制。肾上腺静脉血采样和静脉造影提示左肾上腺腺瘤存在,手术探查和病理检查证实了这一点。肾上腺切除术后所有临床和生化异常均得到纠正。本文讨论了在这种临床情况下各种类型醛固酮增多症和/或低钾血症的鉴别诊断。

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1
Childhood primary aldosteronism due to an adrenal adenoma: preoperative localization by adrenal vein catheterization.肾上腺腺瘤所致儿童原发性醛固酮增多症:肾上腺静脉插管术前定位
Pediatrics. 1980 Mar;65(3):605-9.
2
Primary aldosteronism is comprised of primary adrenal hyperplasia and adenoma.原发性醛固酮增多症包括原发性肾上腺增生和腺瘤。
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Adrenal vein sampling for primary aldosteronism: the assessment of selectivity and lateralization of aldosterone excess baseline and after adrenocorticotropic hormone (ACTH) stimulation.原发性醛固酮增多症的肾上腺静脉采血:评估醛固酮过量的选择性和侧别化,包括基线水平及促肾上腺皮质激素(ACTH)刺激后情况。
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[Conceptual basis and diagnosis of primary hyperaldosteronism].[原发性醛固酮增多症的概念基础与诊断]
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Clinical manifestation of aldosteronoma.醛固酮瘤的临床表现。
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[Adrenal vein catheterization in primary hyperaldosteronism: aid in surgical decision making?].
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Adrenal histologic findings show no difference in clinical presentation and outcome in primary hyperaldosteronism.肾上腺组织学发现显示原发性醛固酮增多症的临床表现和结局无差异。
Ann Surg Oncol. 2013 Mar;20(3):753-8. doi: 10.1245/s10434-012-2670-2. Epub 2012 Oct 23.
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Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.一名11岁儿童的分泌醛固酮的肾上腺皮质腺瘤及文献综述
Eur J Pediatr. 1994 Jul;153(7):480-2. doi: 10.1007/BF01957000.
5
Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.一名11岁儿童的醛固酮分泌性肾上腺皮质腺瘤及文献综述
Eur J Pediatr. 1994 Oct;153(10):715-7. doi: 10.1007/BF01954485.
6
Primary hyperaldosteronism due to an adrenal adenoma in a 14-year-old boy.一名14岁男孩因肾上腺腺瘤导致原发性醛固酮增多症。
Postgrad Med J. 1995 Feb;71(832):104-6. doi: 10.1136/pgmj.71.832.104.
7
Adrenal carcinoma and adenoma in children: a review of 17 patients.儿童肾上腺皮质癌和腺瘤:17例病例回顾
Pediatr Radiol. 1983;13(1):11-8. doi: 10.1007/BF00975660.
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CT localization of an aldosteronoma in a 10-year-old boy.一名10岁男孩醛固酮瘤的CT定位
Pediatr Radiol. 1986;16(1):85-6. doi: 10.1007/BF02387519.
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Pediatric hypertension: an approach to imaging.小儿高血压:影像学检查方法
Pediatr Radiol. 1986;16(6):461-7. doi: 10.1007/BF02387958.
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Low-renin hypertension of childhood.儿童低肾素性高血压
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