Tong D, Griffin T W, Laramore G E, Kurtz J M, Russell A H, Groudine M T, Herron T, Blasko J C, Tesh D W
Radiology. 1980 Apr;135(1):195-8. doi: 10.1148/radiology.135.1.7360960.
Between 1956 and 1978, nine patients with solitary plasmacytoma of bone (SPB) and seven with extramedullary plasmacytoma (EMP) were treated at the University of Washington Hospital and Swedish Tumor Institute. All but one patient had local radiotherapy. In the SPB group, six of nine patients progressed to multiple myeloma (MM) and five died of disease within three years after dissemination. Three of the nine patients are alive at 5, 8, and 16 years, respectively. In the EMP group, none of the seven patients progressed to MM. Five are alive 16 months to 23 years after radiotherapy. Since there are no reliable criteria for prospectively distinguishing true solitary plasmacytoma from occult MM, all patients with apparently isolated plasmacytoma should receive local radiotherapy with curative intent.
1956年至1978年间，华盛顿大学医院和瑞典肿瘤研究所对9例骨孤立性浆细胞瘤（SPB）患者和7例髓外浆细胞瘤（EMP）患者进行了治疗。除1例患者外，其余均接受了局部放疗。在SPB组中，9例患者中有6例进展为多发性骨髓瘤（MM），5例在播散后3年内死于该疾病。9例患者中有3例分别存活了5年、8年和16年。在EMP组中，7例患者均未进展为MM。5例患者在放疗后存活了16个月至23年。由于目前尚无可靠的标准来前瞻性地区分真正的孤立性浆细胞瘤与隐匿性MM，因此所有明显孤立性浆细胞瘤患者均应接受旨在治愈的局部放疗。
