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再感染性肺结核:一名耐药性疾病患者家庭中的两例病例

Reinfection tuberculosis: two cases in the family of a patient with drug-resistant disease.

作者信息

Ormerod P, Skinner C

出版信息

Thorax. 1980 Jan;35(1):56-9. doi: 10.1136/thx.35.1.56.

Abstract

A 42-year-old housewife died of drug-resistant pulmonary tuberculosis. Two sons had earlier completed a course of treatment for drug-sensitive disease. Six months after her death both sons developed sputum-positive tuberculosis with a drug resistance pattern identical to that of their mother during her last year of life, and including resistance to drugs which neither son had received. In both cases immunocompetence to tuberculin was shown so that reinfection arose purely as a result of heavy exposure.

摘要

一名42岁的家庭主妇死于耐药性肺结核。她的两个儿子早些时候完成了针对药物敏感型疾病的疗程。在她去世六个月后,两个儿子都出现了痰涂片阳性肺结核,耐药模式与他们母亲生命最后一年的相同,包括对两个儿子都未曾使用过的药物产生耐药。在这两个病例中,结核菌素免疫能力均显示正常,因此再次感染纯粹是由于大量接触所致。

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Infection with drug-resistant tubercle bacilli.感染耐药结核杆菌。
Lancet. 1954 Jun 26;266(6826):1308-10. doi: 10.1016/s0140-6736(54)92205-9.
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Exogenous reinfection in tuberculosis.结核病中的外源性再感染
Am Rev Respir Dis. 1970 Jun;101(6):923-7. doi: 10.1164/arrd.1970.101.6.923.

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