Faling L J, Haesaert S P, Elihu C T, Schimmel E M
Arch Intern Med. 1980 Apr;140(4):489-91.
We describe two patients with benign esophageal stricture in whom exfoliative esophageal cytologic features positive for squamous cell carcinoma is attributed to roentgenographically occult lung cancer. The discovery of alveolar macrophages within the esophageal washings of these patients prompted a retrospective analysis assessing the prevalence of esophageal washings contaminated by cellular material from the lower respiratory tract. Alveolar macrophages were observed in 11 of 28 patients (39%) and in 12 of 33 specimens (36%). Alveolar macrophages were noted in half of patients with benign esophageal disease, but in only one of eight cases with proved esophageal cancer. Criteria alerting physicians to the coexistence of benign esophageal stricture and occult respiratory neoplasm are given, and recommendations for a change in reporting esophageal cytologic features are proposed.
我们描述了两名患有良性食管狭窄的患者，其食管脱落细胞学特征显示鳞状细胞癌呈阳性，这归因于X线检查隐匿的肺癌。在这些患者的食管冲洗液中发现肺泡巨噬细胞后，我们进行了一项回顾性分析，以评估被下呼吸道细胞物质污染的食管冲洗液的发生率。在28名患者中的11名（39%）以及33份标本中的12份（36%）观察到了肺泡巨噬细胞。在一半的良性食管疾病患者中发现了肺泡巨噬细胞，但在8例经证实的食管癌患者中仅1例发现。文中给出了提醒医生注意良性食管狭窄与隐匿性呼吸道肿瘤并存的标准，并提出了改变食管细胞学特征报告方式的建议。
