McNamara T E, Butkus D E
Arch Intern Med. 1980 Apr;140(4):494-7.
A retrospective study was undertaken to determine the effects of nephrostomy on renal function in 11 patients with either bilateral ureteral obstruction (nine) or obstruction of a solitary kidney (two) due to advanced metastatic malignancy of nonurologic cause. Nephrostomy resulted in substantial improvement in renal function and lowering of blood pressure. The BUN and serum creatinine levels decreased from 80 +/- 32 and 12.1 +/- 6.3 mg/dL to 34 +/- 24 and 2.4 +/- 2.0 mg/dL, respectively. Mean arterial blood pressure decreased from 112 +/- 22 to 88 +/- 6 mm Hg and correlated significantly with weight loss. Mean patient survival after nephrostomy was 6.7 months. The major complications of nephrostomy included hemorrhage and infection. Nephrostomy resulted in significant improvement in renal function and blood pressure in this group of patients and might add to length of patient survival.
进行了一项回顾性研究，以确定肾造瘘术对11例因非泌尿系统原因的晚期转移性恶性肿瘤导致双侧输尿管梗阻（9例）或孤立肾梗阻（2例）患者肾功能的影响。肾造瘘术使肾功能得到显著改善，血压降低。血尿素氮（BUN）和血清肌酐水平分别从80±32和12.1±6.3mg/dL降至34±24和2.4±2.0mg/dL。平均动脉血压从112±22降至88±6mmHg，且与体重减轻显著相关。肾造瘘术后患者的平均生存期为6.7个月。肾造瘘术的主要并发症包括出血和感染。肾造瘘术使该组患者的肾功能和血压得到显著改善，可能会延长患者的生存期。
