Gilberstadt S J, Gilberstadt H, Zieve L, Buegel B, Collier R O, McClain C J
Arch Intern Med. 1980 Apr;140(4):519-21.
Psychometric tests were administered to 36 alcoholic patients with cirrhosis without overt portal systemic encephalopathy and to 32 alcoholics without liver diseases. Verbal ability was preserved in both groups. The cirrhotic patients scored worse than the alcoholics without liver disease on most of the tests of psychomotor performance. Based on the three most discriminative tests, 50% of the cirrhotic patients had one or more scores that were more abnormal than those of any member of the alcoholic group. Significant correlations were found between the severity of liver disease and most tests of performance in the cirrhotic group, due primarily to the influence of serum albumin as a component of the severity index. We conclude that psychomotor tests are sensitive tools for the detection of latent encephalopathy, and that nutritional status probably plays a role in determining test performance.
对36名患有肝硬化但无明显门体性脑病的酒精性患者和32名无肝脏疾病的酗酒者进行了心理测量测试。两组的语言能力均保持正常。在大多数心理运动表现测试中，肝硬化患者的得分低于无肝脏疾病的酗酒者。基于三项最具区分性的测试，50%的肝硬化患者有一个或多个得分比酗酒组的任何成员都更异常。在肝硬化组中，发现肝脏疾病的严重程度与大多数表现测试之间存在显著相关性，这主要是由于血清白蛋白作为严重程度指数的一个组成部分的影响。我们得出结论，心理运动测试是检测潜在脑病的敏感工具，并且营养状况可能在决定测试表现中起作用。
