Briggs M H
Aust Fam Physician. 1980 Feb;Suppl:25-9.
Oestrogens stimulate and increase HDL cholesterol concentration while progestogens decrease it; quite marked differences in effect on HDL can be demonstrated between the various oestrogen-progestogen combinations. Similar differences can be shown in their effect upon blood coagulation factors and upon the renin-angiotensin aldosterone axis. It is suggested that the selection of an oral contraceptive, in terms of cardiovascular risk, can be made from a consideration of comparative biochemical data.
雌激素可刺激并提高高密度脂蛋白胆固醇浓度，而孕激素则会降低该浓度；不同雌激素 - 孕激素组合对高密度脂蛋白的影响存在显著差异。它们对凝血因子以及肾素 - 血管紧张素 - 醛固酮轴的影响也有类似差异。有人认为，就心血管风险而言，可根据比较生化数据来选择口服避孕药。
