关于憩室病患者乙状结肠肌肉异常的观察
Observations on the muscle abnormality of the human sigmoid colon in diverticular disease.
作者信息
Rees B I, Bond J, Spriggs T L, Hughes L E
出版信息
Br J Clin Pharmacol. 1980 Mar;9(3):229-32. doi: 10.1111/j.1365-2125.1980.tb04831.x.
Abstract
1 Pharmacological experiments were performed on circular and longitudinal muscle strips of sigmoid colon from diverticular disease specimens, and their responses compared with those of similar muscle strips from sigmoid colon resected from carcinoma (control). 2 The longitudinal muscle strips from diverticular disease specimens were significantly less responsive to acetylcholine, histamine or noradrenaline than control longitudinal muscle strips. 3 The responses of the diverticular circular muscle strips showed a small decrease to acetylcholine, a small increase to noradrenaline and no change to histamine when compared to control strips.
摘要
- 对来自憩室病标本的乙状结肠环形和纵行肌条进行了药理学实验，并将它们的反应与从癌组织切除的乙状结肠（对照）的相似肌条的反应进行比较。2. 来自憩室病标本的纵行肌条对乙酰胆碱、组胺或去甲肾上腺素的反应明显低于对照纵行肌条。3. 与对照肌条相比，憩室环形肌条对乙酰胆碱的反应略有下降，对去甲肾上腺素的反应略有增加，对组胺无变化。
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