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一种补体第一成分抑制剂活性的估算方法。

A method for the estimation of the activity of the inhibitor of the first component of complement.

作者信息

Smith A M, Thompson R A

出版信息

J Clin Pathol. 1980 Feb;33(2):167-70. doi: 10.1136/jcp.33.2.167.

Abstract

The activated first component of complement (CI) possesses an esterase activity in vitro which will hydrolyse an ester of tyrosine to release H+. The activity of the serum inhibitor of C1 esterase may be measured by monitoring its ability to prevent H+ release under standard conditions. This paper describes a method of measuring such activity, monitoring H+ release by the use of either an acid base indicator of pH meter.

摘要

活化的补体第一成分(C1)在体外具有酯酶活性,它能水解酪氨酸酯以释放H⁺。C1酯酶血清抑制剂的活性可通过监测其在标准条件下阻止H⁺释放的能力来测定。本文描述了一种测量这种活性的方法,即使用酸碱指示剂或pH计监测H⁺的释放。

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