Froom J, Mold J, Culpepper L, Boisseau V
J Fam Pract. 1980 Apr;10(4):599-605.
Individual and family factors which relate to acute purulent otitis media were investigated in a family practice population. In a practice with more than 11,000 patients, 442 persons had 527 episodes of otitis media during a one-year period. More than 20 percent of the cases occurred in patients of age 15 years and over, but the case rate per year for this group was 11 cases per 1,000 as opposed to 109.7 cases per 1,000 for patients under the age of 15 years. Twenty percent of young children had two or more episodes during the year as compared with five percent for adults. Females had more multiple episodes than did males. The incidence of multiple cases in families is greater than would be expected if cases were distributed randomly (P less than 0.05). However, significantly fewer families with three or more children reported cases of otitis media as compared with smaller families (P less than 0.05).
在一个家庭医疗人群中，对与急性化脓性中耳炎相关的个人和家庭因素进行了调查。在一个拥有超过11000名患者的医疗机构中，442人在一年时间里发生了527次中耳炎发作。超过20%的病例发生在15岁及以上的患者中，但该组每年的发病率为每1000人中有11例，而15岁以下患者的发病率为每1000人中有109.7例。20%的幼儿在这一年中有两次或更多次发作，而成人的这一比例为5%。女性的多次发作比男性更多。家庭中多例病例的发生率高于病例随机分布时的预期发生率（P小于0.05）。然而，与小家庭相比，有三个或更多孩子的家庭报告的中耳炎病例明显更少（P小于0.05）。
