Babich H, Stotzky G
Appl Environ Microbiol. 1978 Dec;36(6):906-14. doi: 10.1128/aem.36.6.906-914.1978.
A 10 mM concentration of Zn2+ decreased the survival of Escherichia coli; enhanced the survival of Bacillus cereus; did not significantly affect the survival of Pseudomonas aeruginosa, Norcardia corallina, and T1, T7, P1, and phi80 coliphages; completely inhibited mycelial growth of Rhizoctonia solani; and reduced mycelial growth of Fusarium solani, Cunninghamella echinulata, Aspergillus niger, and Trichoderma viride. The toxicity of zinc to the fungi, bacteria, and coliphages was unaffected, lessened, or increased by the addition of high concentrations of NaCl. The increased toxicity of zinc in the presence of high concentrations of NaCl was not a result of a synergistic interaction between Zn2+ and elevated osmotic pressures but of the formation of complex anionic ZnCl species that exerted greater toxicities than did cationic Zn2+. Conversely, the decrease in zinc toxicity with increasing concentrations of NaCl probably reflected the decrease in the levels of Zn2+ due to the formation of Zn-Cl species, which was less inhibitory to these microbes than was Zn2+. A. niger tolerated higher concentrations of zinc in the presence of NaCl at 37 than at 25 degrees C.
10毫摩尔浓度的锌离子可降低大肠杆菌的存活率；提高蜡样芽孢杆菌的存活率；对铜绿假单胞菌、珊瑚诺卡氏菌以及T1、T7、P1和φ80大肠杆菌噬菌体的存活率无显著影响；完全抑制茄丝核菌的菌丝生长；并减少茄腐镰刀菌、刺孢小克银汉霉、黑曲霉和绿色木霉的菌丝生长。添加高浓度氯化钠后，锌对真菌、细菌和噬菌体的毒性不受影响、减弱或增强。在高浓度氯化钠存在的情况下，锌毒性增加并非锌离子与渗透压升高之间协同作用的结果，而是形成了毒性比阳离子锌离子更大的复合阴离子氯化锌物种。相反，随着氯化钠浓度增加锌毒性降低，可能反映了由于形成锌 - 氯物种导致锌离子水平下降，而锌 - 氯物种对这些微生物的抑制作用小于锌离子。在37℃时，黑曲霉在氯化钠存在的情况下比在25℃时能耐受更高浓度的锌。
