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猝死与肝脏脂肪变性。北卡罗来纳州的一项调查。

Sudden death and hepatic fatty metamorphosis. A North Carolina survey.

作者信息

Randall B

出版信息

JAMA. 1980 May 2;243(17):1723-5.

PMID:7365935
Abstract

There is a generally unrecognized epidemic of sudden, nonviolent deaths among alcohol abusers, largely due to fatty liver--related sudden deaths (FLDs). Using data from the North Carolina Office of the Chief Medical Examiner, 411 cases of FLD were identified from 1972 through 1976. The 411 FLD deaths, in view of a low autopsy rate among nonviolent alcohol abuser deaths and the lack of awareness of FLD, suggest a FLD death rate of epidemic proportions. The FLD population characteristics mirror those of the underlying alcohol-abusing population. The increased incidence of low-level (1 to 50 mg/dL) blood ethanol levels among FLD as compared with "control" groups is consistent with several theories linking FLD to some form of acute or hyperacute ethanol withdrawal phenomenon.

摘要

在酗酒者中,存在一种普遍未被认识到的突发性、非暴力死亡的流行情况,这主要归因于与脂肪肝相关的猝死(FLD)。利用北卡罗来纳州首席法医办公室的数据,从1972年到1976年共识别出411例FLD病例。鉴于非暴力酗酒者死亡的尸检率较低以及对FLD缺乏认识,这411例FLD死亡表明其死亡率达到了流行程度。FLD人群特征反映了潜在酗酒人群的特征。与“对照组”相比,FLD患者中低水平(1至50毫克/分升)血液乙醇水平的发病率增加,这与几种将FLD与某种形式的急性或超急性乙醇戒断现象联系起来的理论相一致。

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