Ishikawa T, Okajima M, Nimi N, Koike Y, Toyama J, Yamada K
Jpn Circ J. 1980 Feb;44(2):128-36. doi: 10.1253/jcj.44.128.
Simulation by a digital computer of excitation spread in a human ventricular model produced displays of body surface isopotential maps. Localization of model myocardial infarctions to non-transmural and transmural sites produced distinctive differences in these displayed isopotential maps. The body surface directly over the infarcted lesion was negative in potential only in the first half period of the QRS complex and then became positive. The model demonstrated that this later positive potential was due to delayed arrival of excitation to the subepicardial layer outside of the subendocardial lesion. While, in transmural infarction, the overlying body surface remained negative in potential throughout the QRS complex. It is expected that body surface isopotential maps will become clinically available and will permit helpful differential diagnoses between non-transumral and transmural myocardial infarctions.
通过数字计算机对人体心室模型中的兴奋传播进行模拟，生成了体表等电位图。将模型心肌梗死定位到非透壁和透壁部位，在这些显示的等电位图中产生了明显的差异。梗死病变正上方的体表仅在QRS波群的前半周期电位为负，然后变为正。该模型表明，这种后期的正电位是由于兴奋延迟到达心内膜下病变外的心外膜下层。而在透壁梗死中，覆盖的体表在整个QRS波群期间电位仍为负。预计体表等电位图将在临床上可用，并将有助于对非透壁和透壁心肌梗死进行鉴别诊断。
