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化脓性心包炎的临床与细菌学方面(作者译)

[Clinical and bacteriological aspects of purulent pericarditis (author's transl)].

作者信息

Vilaseca J, Arnau J M, Galve E, Torrabadella P, Murillo F

出版信息

Med Clin (Barc). 1980 Mar 25;74(6):222-5.

PMID:7366284
Abstract

The clinical and bacteriological characteristics of eight cases with purulent pericarditis observed over the last five years are studied. The route of the infection and dissemination in the majority of the cases (75 percent) was through pleuropulmonary lesions in the form of pneumonia and/or empyema, attributing the remaining cases to a subhepatic abscess and a pericardial infection after a thoracic surgical operation. In seven patients the diagnosis of the disease was established while they were alive. The more orientative clinical data were the pericardial pain (50 percent), pericardial friction murmur (25 percent), and signs of cardiac tamponade (62.5 percent). The observation of the above mentioned clinical signs together with the presence of cardiomegaly and electrocardiographic alterations suggestive of pericarditis, obliged the practice of a pericardial puncture, which confirmed the diagnosis of a purulent pericarditis by the macro and microscopic characteristics of the fluid. Staphylococcus and pneumoncoccus were isolated in two cases, respectively; other Gram-negative bacillus (E. coli and Pseudomonas aeruginosa) were isolated in the remaining cases. All patients were treated with the appropriate antibiotic according to the isolated germ; surgical drainage was carried out in six cases, and a pericardiectomy in one. Two patients died, one as a consequence of a septic myocardiopathy and the other in which the diagnosis of purulent pericarditis was not clinically suspected. During the follow-up period one case presented a constrictive pericarditis, which was corrected by a pericardiectomy.

摘要

研究了过去五年中观察到的八例化脓性心包炎患者的临床和细菌学特征。在大多数病例(75%)中,感染和传播途径是通过肺炎和/或脓胸形式的胸膜肺部病变,其余病例归因于肝下脓肿和胸外科手术后的心包感染。七名患者在生前确诊。更具指示性的临床数据是心包疼痛(50%)、心包摩擦音(25%)和心脏压塞体征(62.5%)。上述临床体征加上心脏扩大和提示心包炎的心电图改变,促使进行心包穿刺,根据穿刺液的宏观和微观特征证实了化脓性心包炎的诊断。分别在两例中分离出葡萄球菌和肺炎球菌;其余病例分离出其他革兰氏阴性杆菌(大肠杆菌和铜绿假单胞菌)。所有患者均根据分离出的病菌使用适当的抗生素进行治疗;六例进行了手术引流,一例进行了心包切除术。两名患者死亡,一名死于感染性心肌病,另一名在临床上未怀疑化脓性心包炎。在随访期间,一例出现缩窄性心包炎,通过心包切除术得到纠正。

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