Chaplin E R, Goldstein G W, Myerberg D Z, Hunt J V, Tooley W H
Pediatrics. 1980 May;65(5):901-9.
Between 1969 and 1978 we treated 22 low birth weight infants for delayed onset posthemorrhagic hydrocephalus. All developed clinical signs of hydrocephalus after 2 weeks of age. The diagnosis was determined in 12 infants before August 1974, and they were treated by surgical placement of a shunt. In the ten infants born after September 1974, an attempt was first made to control the hydrocephalus with repeated lumbar puncture and diuretics prior to placing a shunt. In seven of the ten the hydrocephalus was successfully arrested by medical therapy alone. Follow-up assessments at 1 to 8 years of age were done on 18 infants. Two of the 12 treated by permanent shunts and three of six treated medically had an IQ score of 85 or greater. These results indicate a poor long-term outlook for the low birth weight infant who develops clinically overt hydrocephalus after intracranial bleeding.
1969年至1978年间,我们对22例低体重出生的婴儿进行了治疗,这些婴儿患有出血后迟发性脑积水。所有婴儿在2周龄后均出现了脑积水的临床症状。1974年8月前,12例婴儿确诊后接受了分流手术治疗。1974年9月后出生的10例婴儿,在进行分流手术前,首先尝试通过反复腰椎穿刺和使用利尿剂来控制脑积水。10例中有7例仅通过药物治疗就成功控制了脑积水。我们对18例婴儿进行了1至8岁的随访评估。接受永久性分流手术治疗的12例中,有2例,接受药物治疗的6例中有3例智商得分在85分及以上。这些结果表明,颅内出血后出现临床明显脑积水的低体重出生婴儿远期预后较差。