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偏瘫性痉挛:神经生理学研究

Hemiplegic spasticity: neurophysiologic studies.

作者信息

Somerville J, Ashby P

出版信息

Arch Phys Med Rehabil. 1978 Dec;59(12):592-6.

PMID:736764
Abstract

The excitability of segmental reflex pathways in normal subjects and in patients with hemiplegia has been examined by conditioning the monosynaptic H reflex with a 200 msec burst of vibration applied to the tendo Achilles. In 6 normal subjects, the burst of vibration produced a short-latency facilitation of soleus motoneurons (attributed to monosynaptic excitation) which was followed by a longer-latency inhibition. A similar response was observed in 8 patients with hemiplegia, but the late inhibition was significantly less. The loss of an inhibitory mechanism may contribute to the exaggerated reflexes observed in patients with hemiplegia.

摘要

通过对跟腱施加200毫秒的振动脉冲来条件化单突触H反射,研究了正常受试者和偏瘫患者节段性反射通路的兴奋性。在6名正常受试者中,振动脉冲产生了比目鱼肌运动神经元的短潜伏期易化(归因于单突触兴奋),随后是较长潜伏期的抑制。在8名偏瘫患者中观察到类似的反应,但后期抑制明显较少。抑制机制的丧失可能导致偏瘫患者出现反射亢进。

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