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偏瘫性痉挛:神经生理学研究

Hemiplegic spasticity: neurophysiologic studies.

作者信息

Somerville J, Ashby P

出版信息

Arch Phys Med Rehabil. 1978 Dec;59(12):592-6.

PMID:736764
Abstract

The excitability of segmental reflex pathways in normal subjects and in patients with hemiplegia has been examined by conditioning the monosynaptic H reflex with a 200 msec burst of vibration applied to the tendo Achilles. In 6 normal subjects, the burst of vibration produced a short-latency facilitation of soleus motoneurons (attributed to monosynaptic excitation) which was followed by a longer-latency inhibition. A similar response was observed in 8 patients with hemiplegia, but the late inhibition was significantly less. The loss of an inhibitory mechanism may contribute to the exaggerated reflexes observed in patients with hemiplegia.

摘要

通过对跟腱施加200毫秒的振动脉冲来条件化单突触H反射,研究了正常受试者和偏瘫患者节段性反射通路的兴奋性。在6名正常受试者中,振动脉冲产生了比目鱼肌运动神经元的短潜伏期易化(归因于单突触兴奋),随后是较长潜伏期的抑制。在8名偏瘫患者中观察到类似的反应,但后期抑制明显较少。抑制机制的丧失可能导致偏瘫患者出现反射亢进。

相似文献

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Hemiplegic spasticity: neurophysiologic studies.偏瘫性痉挛:神经生理学研究
Arch Phys Med Rehabil. 1978 Dec;59(12):592-6.
2
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Neurophysiologic changes in hemiplegia. Possible explanation for the initial disparity between muscle tone and tendon reflexes.偏瘫中的神经生理学变化。肌张力与腱反射初始差异的可能解释。
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Arch Phys Med Rehabil. 2001 Nov;82(11):1604-10. doi: 10.1053/apmr.2001.25081.

引用本文的文献

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Evaluating the differential electrophysiological effects of the focal vibrator on the tendon and muscle belly in healthy people.评估聚焦振动器对健康人群肌腱和肌腹的不同电生理效应。
Ann Rehabil Med. 2014 Aug;38(4):494-505. doi: 10.5535/arm.2014.38.4.494. Epub 2014 Aug 28.
2
Patients with spastic hemiplegia at different recovery stages: evidence of reciprocal modulation of early/late reflex responses.不同恢复阶段的痉挛性偏瘫患者:早期/晚期反射反应相互调节的证据。
J Neurol Neurosurg Psychiatry. 1993 Apr;56(4):386-92. doi: 10.1136/jnnp.56.4.386.
3
Neurophysiological changes following traumatic spinal lesions in man.
人类创伤性脊髓损伤后的神经生理变化。
J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1102-8. doi: 10.1136/jnnp.47.10.1102.
4
Further observations on the depression of group Ia facilitation of motoneurons by vibration in man.关于人体振动对运动神经元Ia类易化作用抑制的进一步观察
Exp Brain Res. 1987;69(1):1-6. doi: 10.1007/BF00247023.
5
Short-latency autogenic inhibition (IB inhibition) in human spasticity.人类痉挛状态下的短潜伏期自发电抑制(Ib抑制)
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1546-50. doi: 10.1136/jnnp.51.12.1546.
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Presynaptic inhibition of monosynaptic reflexes in the lower limbs of subjects with upper motoneuron disease.上运动神经元疾病患者下肢单突触反射的突触前抑制
J Neurol Neurosurg Psychiatry. 1986 Aug;49(8):937-44. doi: 10.1136/jnnp.49.8.937.
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A comparative study of methods for estimation of presynaptic inhibition.突触前抑制评估方法的比较研究
J Neurol. 1992 May;239(5):287-92. doi: 10.1007/BF00810355.