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突触前抑制评估方法的比较研究

A comparative study of methods for estimation of presynaptic inhibition.

作者信息

Milanov I

机构信息

Institute of Neurology, Psychiatry and Neurosurgery, Bulgarian Medical Academy, Sofia.

出版信息

J Neurol. 1992 May;239(5):287-92. doi: 10.1007/BF00810355.

DOI:10.1007/BF00810355
PMID:1607893
Abstract

The influence of vibration on the H-reflex and on the tendon reflex amplitudes was compared and the efficacy of both methods for the assessment of the presynaptic inhibition was studied. One hundred and twenty patients with post-stroke spastic hemiparesis were investigated. Muscle tone, muscle force and tendon reflexes were assessed. The H-reflex and the Achilles tendon reflex (TA) were recorded under identical experimental conditions. Vibration at a frequency of 100 Hz and an amplitude of 2 mm was applied to the TA. Just after vibration the maximal amplitudes of both reflexes were measured. The ratios of reflex amplitudes after vibration to normal maximal reflex amplitudes (Hvibr/Hmax and TAvibr/TAmax) were evaluated. In all patients with hemiparesis the healthy side was used as a control. Our results revealed significantly increased amplitude ratios on the spastic side. Hence it is concluded that presynaptic inhibition is decreased in spasticity. The amplitude ratios on the healthy and the spastic side were consistent. There was good positive correlation between Hvibr/Hmax and TAvibr/TAmax ratios, suggesting that they provide similar and reliable estimates of presynaptic inhibition.

摘要

比较了振动对H反射和腱反射幅度的影响,并研究了这两种方法评估突触前抑制的有效性。对120例中风后痉挛性偏瘫患者进行了研究。评估了肌张力、肌力和腱反射。在相同的实验条件下记录H反射和跟腱反射(TA)。以100Hz的频率和2mm的振幅对TA施加振动。振动刚结束后,测量两种反射的最大幅度。评估振动后反射幅度与正常最大反射幅度的比值(Hvibr/Hmax和TAvibr/TAmax)。在所有偏瘫患者中,将健侧作为对照。我们的结果显示痉挛侧的幅度比值显著增加。因此得出结论,痉挛时突触前抑制降低。健侧和痉挛侧的幅度比值是一致的。Hvibr/Hmax和TAvibr/TAmax比值之间存在良好的正相关,表明它们对突触前抑制提供了相似且可靠的估计。

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H-reflex and vibratory stimuli to the extremity.对肢体的Hoffmann反射(H反射)和振动刺激。
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Dependence of the Achilles tendon reflex on the excitability of spinal reflex pathways.跟腱反射对脊髓反射通路兴奋性的依赖性。
Ann Neurol. 1981 Dec;10(6):551-6. doi: 10.1002/ana.410100610.
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Postsynaptic potentials in individual soleus motoneurons in man produced by achilles tendon taps and electrical stimulation of tibial nerve.跟腱叩击和胫神经电刺激在人体单个比目鱼肌运动神经元中产生的突触后电位。
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Mechanically and electrically elicited monosynaptic reflexes in man.人体中机械和电诱发的单突触反射
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