五种品牌地高辛片的物理和溶出特性及生物利用度
Physical and dissolution characteristics and bio-availability of five brands of digoxin tablets.
作者信息
Fletcher S, Summers R S
出版信息
S Afr Med J. 1980 Apr 5;57(14):530-3.
PMID:7368019
Abstract
Five brands of digoxin were investigated and compared for physical and dissolution characteristics and bio-availability. The dissolution characteristics, which are regarded as a measure of bio-availability in the case of digoxin, were investigated with a spectrofluorimeter. Significant differences were found among the five brands. Only one brand met all the various criteria that were investigated.
摘要
对五个品牌的地高辛进行了物理、溶出特性和生物利用度的研究与比较。使用荧光分光光度计研究了溶出特性，在使用地高辛的情况下，溶出特性被视为生物利用度的一个衡量指标。发现这五个品牌之间存在显著差异。只有一个品牌满足所研究的所有不同标准。
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