[Biochemical and cytokinetic patterns in the growth of a transplanted pigmented melanoma].

Under study were biochemical and cytokinetic patterns of the pigmented melanoma growth in mice. The data obtained allows a conclusion that there is a relationship between the process of melanogenesis and proliferative activity of the tumor tissue. A delayed tumor growth beyond the peak point due to the reduced proliferative pool and increased cell losses is accompanied with a fall in the activity of the key enzyme of melanogenesis and the reduced level of melanoproteids.