Oberhänsli I, Brandon G, Lacourt G, Friedli B
Acta Paediatr Scand. 1980 Mar;69(2):239-47. doi: 10.1111/j.1651-2227.1980.tb07068.x.
A longitudinal study was undertaken in 21 newborns to determine cardiac growth pattern by echocardiography over the course of the first year of life. Most cardiac structures increased in size as a linear function of age and weight; however, the right ventricular end-diastolic diameter remained unchanged so that the RV/LV ratio decreased as a parabolic function of age. Left and right ventricular systolic time intervals (RVSTI, LVSTI) after birth were also studied. The ratio of left ventricular preejection period (LVPEP) to left ventricular ejection time (LVET) decreased markedly immediately after birth and subsequently remained at a constant mean value (0.30 +/- 0.04) for the rest of the study period. Right ventricular systolic time interval ratios (RVPEP/RVET) decreased rapidly and significantly during the first day of life (from a mean value of 0.39 +/- 0.08 in the first 24 hours to 0.28 +/- 0.05 on the 6th day of life). Constant values of 0.24 +/- 0.03 were found from the 3rd month of life onwards. The decrease in RVPEP/RVET in the first days of life followed a parabolic function reflecting the physiological decrease of pulmonary vascular resistance after birth.
对21名新生儿进行了一项纵向研究，以通过超声心动图确定生命第一年中心脏的生长模式。大多数心脏结构的大小随着年龄和体重的线性函数而增加；然而，右心室舒张末期直径保持不变，因此右心室与左心室的比值随着年龄的抛物线函数而降低。还研究了出生后左、右心室收缩时间间期（右心室收缩时间间期、左心室收缩时间间期）。左心室射血前期（LVPEP）与左心室射血时间（LVET）的比值在出生后立即显著下降，随后在研究期的剩余时间内保持在恒定的平均值（0.30±0.04）。右心室收缩时间间期比值（RVPEP/RVET）在出生后第一天迅速且显著下降（从最初24小时的平均值0.39±0.08降至出生后第6天的0.28±0.05）。从出生后第3个月起发现恒定值为0.24±0.03。出生后最初几天RVPEP/RVET的下降遵循抛物线函数，反映了出生后肺血管阻力的生理性下降。
