Siegel S R, Siegel B, Sokoloff B Z, Kanter M H
Am J Dis Child. 1980 Apr;134(4):369-72. doi: 10.1001/archpedi.1980.04490010027010.
A group of 1,617 infants and 1,711 preschool children were studied for symptomatic and asymptomatic urinary infection and followed up for three to five years. Asymptomatic bacteriuria was found in 1.8% of female infants, 0.5% of male infants, 0.8% of preschool girls, and none of the preschool boys. Seventeen percent of the infants and 13% of the preschool children with urinary infection studied roentgenographically had upper tract damage; 46% of the infants and 9% of the preschool children had vesicoureteral reflux. Infants with normal urinary tracts and urinary infection with or without reflux tended to have recurrent infection, whereas the kidneys remained anatomically normal. The infants with high-risk lesions, such as obstructive uropathy and vesicoureteral junction ectopia and deformity, had substantial bacteriuria on screening culture.
对1617名婴儿和1711名学龄前儿童进行了有症状和无症状尿路感染的研究，并随访了三到五年。无症状菌尿在1.8%的女婴、0.5%的男婴、0.8%的学龄前女童中被发现，而学龄前男童中未发现。接受X线检查的尿路感染婴儿中有17%、学龄前儿童中有13%存在上尿路损害；46%的婴儿和9%的学龄前儿童有膀胱输尿管反流。尿路正常的婴儿无论有无反流发生尿路感染后往往会复发感染，而肾脏在解剖结构上保持正常。有高危病变的婴儿，如梗阻性尿路病、膀胱输尿管连接部异位和畸形，在筛查培养时有大量菌尿。
