Kuberski T, Koteka G
Am J Trop Med Hyg. 1980 Mar;29(2):291-7. doi: 10.4269/ajtmh.1980.29.291.
A sudden outbreak of skin ulcers occurred in the Cook Islands beginning in early 1976. Information from the outbreak indicated that ulcers were most consistent with the clinical entity of tropical ulcer. A retrospective analysis was undertaken to determine the clinical and epidemiological features of the outbreak. The ulcers occurred most commonly in males in the 10--14 and 15--19 age groups. Antecedent trauma appeared to initiate the ulcer. Most ulcers were solitary, occurred on the lower limbs, and healed leaving a pigmented scar. The ulcers responded well to penicillin. The cause of the ulcers was not established, but gram-negative, pleomorphic bacilli were consistently observed in ulcer biopsies.
1976年初,库克群岛突然爆发皮肤溃疡。此次疫情的信息表明,溃疡与热带溃疡的临床特征最为相符。进行了一项回顾性分析,以确定此次疫情的临床和流行病学特征。溃疡最常发生在10至14岁和15至19岁年龄组的男性中。先前的创伤似乎引发了溃疡。大多数溃疡为单发,发生在下肢,愈合后留下色素沉着疤痕。这些溃疡对青霉素反应良好。溃疡的病因尚未确定,但在溃疡活检中始终观察到革兰氏阴性、多形性杆菌。