The inhibition of dihydrofolate reductase by folate analogues: structural requirements for slow- and tight-binding inhibition.

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作者信息

Williams J W, Duggleby R G, Cutler R, Morrison J F

出版信息

Biochem Pharmacol. 1980 Feb 15;29(4):589-95. doi: 10.1016/0006-2952(80)90381-0.

DOI:10.1016/0006-2952(80)90381-0

PMID:7370052

Abstract

摘要

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The inhibition of dihydrofolate reductase by folate analogues: structural requirements for slow- and tight-binding inhibition.

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