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骨基质吸收的诱导与抑制

Induction and inhibition of bone matrix resorption.

作者信息

Rebut-Bonneton C, Pasquier C, Delbarre F

出版信息

Biomedicine. 1980 Feb;33(1):26-9.

PMID:7370385
Abstract

A method is described by which the action of hormones on cartilage and bone matrix in mice is ascertained by measuring 35S release from bone explants. Parathyroid extract was found to increase the rate of 35S release in vitro as well as in samples from pretreated animals, whereas calcitonin and 25-hydroxycholecalciferol were effective only in vitro.

摘要

本文描述了一种方法,通过测量骨外植体中35S的释放来确定激素对小鼠软骨和骨基质的作用。发现甲状旁腺提取物在体外以及预处理动物的样本中均可提高35S的释放速率,而降钙素和25-羟基胆钙化醇仅在体外有效。

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