[破伤风毒素对大鼠脑突触体去甲肾上腺素释放的影响]
[Effect of tetanus toxin on noradrenaline release from rat brain synaptosomes].
作者信息
Kryzhanovskiĭ G N, Rodina V I, Glebov R N, Bazian A S
出版信息
Biull Eksp Biol Med. 1980 Feb;89(2):148-50.
PMID:7370409
Abstract
Purified tetanus toxin (TT) (80-800 Dlm/mg protein) releases both endogenous and exogenous (14)C-norepinephrine from the isolated nerve endings (synaptosomes) of the rat brain. Within the investigated range of concentrations TT does not suppress norepinephrine release induced by different ways of depolarizing the synaptosomes in vitro.
摘要
纯化的破伤风毒素（TT）（80 - 800 Dlm/毫克蛋白质）可促使大鼠脑分离神经末梢（突触体）释放内源性和外源性的[¹⁴C]去甲肾上腺素。在研究的浓度范围内，TT不会抑制体外通过不同方式使突触体去极化所诱导的去甲肾上腺素释放。
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