男性泌乳素分泌型垂体腺瘤：经蝶窦显微手术治疗
Prolactin-secreting pituitary adenomas in males: transsphenoidal microsurgical treatment.
作者信息
Serri O, Somma M, Rasio E, Beauregard H, Hardy J
出版信息
Can Med Assoc J. 1980 May 10;122(9):1007-13.
Fifteen male patients with prolactin-secreting pituitary adenomas were studied before and after transsphenoidal microsurgical treatment. Loss of libido and sexual impotence were the most frequent symptoms, being present in 12. Visual defects were present in seven patients, gynecomastia was observed in four and galactorrhea was noted in three. Most of the tumours were large; only one was a microadenoma. Four patients were cured by the operation. In all the other patients the plasma levels of prolactin were significantly lowered and the visual defects corrected or lessened, but sexual impotence was not modified. No important deficiency of the pituitary gland was induced by the operation. The results indicate that in males loss of libido and sexual impotence are frequent and early manifestations of prolactinomas, and that transsphenoidal resection is a safe therapeutic approach.
对15例分泌催乳素的垂体腺瘤男性患者在经蝶窦显微手术治疗前后进行了研究。性欲减退和阳痿是最常见的症状，12例患者存在这些症状。7例患者有视觉缺陷，4例观察到男性乳房发育，3例有溢乳现象。大多数肿瘤较大；只有1例是微腺瘤。4例患者手术治愈。在所有其他患者中，催乳素血浆水平显著降低，视觉缺陷得到纠正或减轻，但阳痿没有改善。手术未引起重要的垂体功能减退。结果表明，在男性中，性欲减退和阳痿是催乳素瘤常见的早期表现，经蝶窦切除术是一种安全的治疗方法。
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