用于血池研究的锝-99m标记人血清白蛋白与体外标记红细胞的比较。
A comparison of Tc-99m-labeled human serum albumin and in vitro labeled red blood cells for blood pool studies.
作者信息
Atkins H L, Klopper J F, Ansari A N, Meinken G, Richards P, Srivastava S C
出版信息
Clin Nucl Med. 1980 Apr;5(4):166-9. doi: 10.1097/00003072-198004000-00007.
A comparison of Tc-99m-labeled human serum albumin (HSA) and in vitro labeled red blood cells (RBC) was carried out in five subjects. The disappearance of radioactivity from the blood was more rapid for HSA (T 1/2, 281.6 minutes, range 202.1--318.3) than for RBC (T 1/2, 1719.8 minutes, range 767.6--5059.5). Urinary excretion was twice as great for HSA. Ratios of activity in heart blood pool to lung and liver were considerably greater for RBC up to 2 hours after administration. The results indicate that labeled RBC are superior to labeled HSA for blood pool imaging.
对5名受试者进行了锝-99m标记的人血清白蛋白（HSA）和体外标记红细胞（RBC）的比较。HSA从血液中放射性的消失比RBC更快（HSA的半衰期为281.6分钟，范围为202.1 - 318.3分钟；RBC的半衰期为1719.8分钟，范围为767.6 - 5059.5分钟）。HSA的尿排泄量是RBC的两倍。给药后长达2小时，RBC在心血池与肺和肝脏中的活性比要高得多。结果表明，标记红细胞在血池显像方面优于标记人血清白蛋白。
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