大剂量维生素C对血清和尿草酸的影响。
Effect of megadoses of ascorbic acid on serum and urinary oxalate.
作者信息
Hatch M, Mulgrew S, Bourke E, Keogh B, Costello J
出版信息
Eur Urol. 1980;6(3):166-9. doi: 10.1159/000473318.
PMID:7371664
Abstract
Serum and urinary oxalate was determined in 9 normal subjects, ingesting 8 g of ascorbic acid daily. Serum oxalate levels increased to 310% of control values during supplementation. Plasma ascrobate levels reached a mean value of 3.6 mg% far exceeding the previously reported plateau level of 1.8 mg%. Urinary oxalate gradually increased during ascorbate intake and 7 days post cessation of ascorbate, rose unexpectedly for all subjects into the hyperoxaluric range.
摘要
对9名正常受试者进行了血清和尿草酸盐测定，这些受试者每天摄入8克抗坏血酸。在补充期间，血清草酸盐水平升至对照值的310%。血浆抗坏血酸盐水平达到平均3.6mg%，远远超过先前报道的1.8mg%的稳定水平。在摄入抗坏血酸期间，尿草酸盐逐渐增加，在停止摄入抗坏血酸7天后，所有受试者的尿草酸盐意外升至高草酸尿范围。
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