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小鼠肝脏中皮质酮的分解代谢：基因型与饮食之间的相互作用。

Corticosterone catabolism by mouse liver: interactions between genotype and diet.

作者信息

Shire J G

出版信息

Horm Metab Res. 1980 Mar;12(3):117-9. doi: 10.1055/s-2007-996217.

DOI:10.1055/s-2007-996217
PMID:7372271
Abstract

Corticosterone reduction was greater in liver homogenates from C57BL/10ScSn mice than in homogenates from DBA/2J mice. The reactions were stimulated to the same extent by the addition of an NADPH-generating system when the mice had been on a 4% fat diet. When the mice had been on a fat-free diet for 3 days, the generating system produced a much greater effect on homogenates from DBA mice. C57BL/Tb mice resembled C67BL/10ScSn mice with CBA/FaCam mice were similar to DBA/2J mice.

摘要

C57BL/10ScSn小鼠肝脏匀浆中皮质酮的降低幅度大于DBA/2J小鼠匀浆中的降低幅度。当小鼠食用4%脂肪饮食时，添加NADPH生成系统可使反应受到相同程度的刺激。当小鼠食用无脂肪饮食3天时，该生成系统对DBA小鼠的匀浆产生的影响要大得多。C57BL/Tb小鼠与C67BL/10ScSn小鼠相似，而CBA/FaCam小鼠与DBA/2J小鼠相似。

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引用本文的文献

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Corticosterone catabolism by mouse liver homogenate: strain difference in dependence on added NADP.小鼠肝脏匀浆对皮质酮的分解代谢：添加烟酰胺腺嘌呤二核苷酸磷酸（NADP）时的品系差异
J Endocrinol Invest. 1981 Apr-Jun;4(2):193-6. doi: 10.1007/BF03350451.
2
Persistent inverse maternal effect on corticosterone production in vitro.
Experientia. 1984 Sep 15;40(9):1000-1. doi: 10.1007/BF01946479.