Geisler C D, Mountain D C, Hubbard A E
J Acoust Soc Am. 1980 May;67(5):1729-35. doi: 10.1121/1.384299.
A new technique for measuring sound-induced resistance changes (CR) in scala media in response to pure-tone stimuli by injecting alternating current into guinea-pig cochleas was reported recently [C.D. Geisler et al., J. Acoust. Soc. Am. 61, 1557-1566 (1977)]. Detailed measurements with this technique indicate that while the CR behaves approximately as does the cochlear microphonic (CM) there can be very significant differences between the two variables under certain experimental conditions. Computer analysis of simultaneously recorded CR voltage components and CM indicates that the CR harmonics, in both amplitude and phase, behaved differently with sound intensity and with asphyxia than did the CM harmonies (A.E. Hubbard et al., J. Acoust. Soc. Am 66, 431-445 (1979)]. Direct current injection and stimulation of the crossed olivocochlear bundle (COCB) indicate further differences between CM and CR (D.C. Mountain, Ph.D. thesis, University of Wisconsin-Madison, 1978). Positive dc caused a relative augmentation of CM that grew with sound intensity, and a relative reduction in CR magnitude that decreased with intensity. Negative dc caused effects of similar magnitude but opposite sign. COCB stimulation caused enhancement of both CM and CR. Present models cannot account quantitatively for these results.
最近报道了一种通过向豚鼠耳蜗注入交流电来测量蜗管中声致电阻变化（CR）以响应纯音刺激的新技术[C.D. 盖斯勒等人，《美国声学学会杂志》61, 1557 - 1566 (1977)]。用该技术进行的详细测量表明，虽然CR的表现与耳蜗微音电位（CM）大致相同，但在某些实验条件下，这两个变量之间可能存在非常显著的差异。对同时记录的CR电压分量和CM进行计算机分析表明，CR谐波在幅度和相位上，与CM谐波相比，随声强和窒息状态的变化表现不同（A.E. 哈伯德等人，《美国声学学会杂志》66, 431 - 445 (1979)）。直流电注入和交叉橄榄耳蜗束（COCB）刺激表明CM和CR之间存在进一步差异（D.C. 芒廷，博士论文，威斯康星大学麦迪逊分校，1978）。正向直流电导致CM相对增强，且随声强增加，而CR幅度相对减小，且随强度降低。负向直流电产生幅度相似但符号相反的效应。COCB刺激导致CM和CR都增强。目前的模型无法对这些结果进行定量解释。
