Kushakovskiĭ M S, Dzakhova S D
Kardiologiia. 1980 Mar;20(3):56-61.
It is shown that the main trend of changes in water homeostasis in complicated myocardial infarction consists in the development of intercellular hypohydration. Three variants of cardiogenic shock are distinguished: (a) normovolemic shock with intercellular hypohydration; (b) hypovolemic shock with intercellular hypohydration; (c) hypovolemic shock without intercellular hypohydration. Acute congestive cardiac insufficiency in most patients occurs without an increase in the volume of interstitial fluid. Approximately 12% of these patients have a reduced volume of circulating plasma. A syndrome of intercellular hyperhydration develops in the presence of satisfactory hemodynamics on the 3rd day after electrical defibrilation in individuals restored to life after clinical death. The VCP/VIF coefficient may serve as an index of the transcapillary flow of fluid and may be used in determining the indications for infusion therapy.
结果表明，复杂心肌梗死时水稳态变化的主要趋势是细胞间脱水的发展。区分出三种心源性休克类型：(a) 细胞间脱水的正常血容量性休克；(b) 细胞间脱水的低血容量性休克；(c) 无细胞间脱水的低血容量性休克。大多数患者的急性充血性心力衰竭发生时，间质液量并无增加。这些患者中约12%的循环血浆量减少。在临床死亡后复苏的个体中，电除颤后第3天血流动力学良好时会出现细胞间水合过多综合征。VCP/VIF系数可作为液体跨毛细血管流动的指标，可用于确定输液治疗的指征。
